Localized Lysosome Exocytosis Helps Breach Tissue Barriers.
نویسندگان
چکیده
Cell invasion across basement membrane barriers is important in both normal development and cancer metastasis. In this issue of Developmental Cell, Naegeli et al. (2017) identify a mechanism for breaching basement membranes. Localized lysosome exocytosis fuels generation of large, invasive cellular protrusions that expand tiny basement membrane openings.
منابع مشابه
Cell Invasion In Vivo via Rapid Exocytosis of a Transient Lysosome-Derived Membrane Domain.
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ورودعنوان ژورنال:
- Developmental cell
دوره 43 4 شماره
صفحات -
تاریخ انتشار 2017